| Singles competition |
| Main Draw A |
| R64 | Vera Carvalho (Northeastern State) def. Simone Simas (Southern Arkansas) 6-2, 6-0 |
| R64 | Maria Popova (Northeastern State) def. Sofia Pignataro (Northwest Mo. State) 7-6 (4-0), 6-7 (0-4), 10-6 |
| R64 | Serena Gill (Southern Arkansas) def. Melissa Vera (Northeastern State) 7-5, 6-2 |
| R64 | Aastha Dargude (Arkansas Tech) def. Kristela Vidnere (Northeastern State) 6-1, 6-3 |
| Round of 32 |
| R32 | Melisa Becerra (Neb.-Kearney) def. Vera Carvalho (Northeastern State) 7-6 (1-0), 6-7 (0-4), 10-8 |
| R32 | Maria Popova (Northeastern State) def. Dana Issabayeva (Newman) 6-1, 6-7 (0-2), 10-8 |
| Round of 16 |
| R16 | F. Hadjigeorgiou (Augustana (SD)) def. Maria Popova (Northeastern State) 6-1, 6-3 |
| Main Draw B |
| R64 | Chantal Lozano (Southeastern Okla.) def. Irene Romero (Northeastern State) 7-5, 6-3 |
| R64 | Belinda Jayaprakash (Northeastern State) def. Thi Huynh (Neb.-Kearney) 6-0, 6-1 |
| Round of 32 |
| R32 | Ariella Curci (Missouri Western St.) def. Belinda Jayaprakash (Northeastern State) 6-3, 6-1 |
| R32 | Melanie Griffiths (Arkansas Tech) def. Aurbrey Bailey (Northeastern State) 6-4, 6-3 |
| R32 | Issabella Pensavalle (Washburn) def. Alisha Moldakhmetova (Northeastern State) 7-6 (3-0), 7-6 (7-0) |
| Main Draw A (Consola |
| Divya Murali (Newman) def. Melissa Vera (Northeastern State) 6-2, 6-2 |
| Narindra Ranaivo (Neb.-Kearney) def. Kristela Vidnere (Northeastern State) 6-2, 6-1 |
| Main Draw B (Consola |
| R32Q | Pranathi Gannavaram (Neb.-Kearney) def. Irene Romero (Northeastern State) 6-3, 6-4 |
| R16 | Alisha Moldakhmetova (Northeastern State) def. Ellie Messenger (Missouri Western St.) 8-0 |
| R16 | Aurbrey Bailey (Northeastern State) def. Aliyah Frederick (Fort Hays St.) 9-7 |
| R8 | Rhythem Aswal (Southeastern Okla.) def. Aurbrey Bailey (Northeastern State) 8-3 |
| R8 | Alisha Moldakhmetova (Northeastern State) def. Lexi Penn (Central Okla.) 8-2 |
| R4 | Rhythem Aswal (Southeastern Okla.) def. Alisha Moldakhmetova (Northeastern State) 8-3 |
| Doubles competition |
| Main Draw A |
| R32 | Claudia Iglesias/Esther Guemes (Missouri Western St.) def. Kristela Vidnere/Maria Popova (Northeastern State) 8-3 |
| R32 | Daniela Baez/Lea Grinberg (Arkansas Tech) def. Melissa Vera/Vera Carvalho (Northeastern State) 8-1 |
| Main Draw A (Consola |
| R16Q | Kristela Vidnere/Maria Popova (Northeastern State) def. Maria Paz Diaz/Stefany Stemmer (Fort Hays St.) 6-0 |
| R16Q | Kristela Vidnere/Maria Popova (Northeastern State) def. Allison Carpenter/Lindy Carpenter (Harding) 7-6 (7-0) |
| C-QF | Kristela Vidnere/Maria Popova (Northeastern State) def. Sydnee Foster/Cadence Lynn (Washburn), walkover |
| C-QF | Melissa Vera/Vera Carvalho (Northeastern State) def. Taylor Hansard/Shelly Davilus (Ouachita Baptist) 6-2 |
| C-SF | Alexis Bernthal/Jazmin Zamorano (Neb.-Kearney) def. Kristela Vidnere/Maria Popova (Northeastern State) 6-4 |
| C-SF | Blythe Buntrock/Grace Chadick (Central Okla.) def. Melissa Vera/Vera Carvalho (Northeastern State) 7-5 |
| Main Draw B |
| R32 | Irene Romero/Aurbrey Bailey (Northeastern State) def. Nichole Maldonado/Chantal Lozano (Southeastern Okla.), walkover |
| R16 | Belinda Jayaprakash/Alisha Moldakhmetova (Northeastern State) def. Carla Gallart/Keelan Williams (Ouachita Baptist) 8-5 |
| R16 | Nicole Donnelly/Ariella Curci (Missouri Western St.) def. Irene Romero/Aurbrey Bailey (Northeastern State) 8-2 |
| QF | Masha Hatouka/Jazmin Zamorano (Neb.-Kearney) def. Belinda Jayaprakash/Alisha Moldakhmetova (Northeastern State) 8-3 |